Endothelial heparanase regulation of cardiac metabolism
Following diabetes, the heart increases its lipoprotein lipase (LPL) at the coronary lumen by transferring LPL from the cardiomyocyte to the endothelial lumen. Heparanase is an endoglycosidase that specifically cleaves carbohydrate chains of heparan sulfate (HS). We examined the mechanisms behind...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/36742 |