Synthesis in the pyridine series : Part 1. The synthesis of new 3,4,5-trialkylated pyridines ; part 2. The synthesis of new 3,5 dimethyl-4-substituted pyridines ; steric effects as an aid to synthesis
PART I A synthetic sequence leading to new and inaccessible 3,4-,5-trialkylated pyridines has been developed 3,4-Dimethyl-5-cyanopyridine was converted to 3,4-dimethyl-5-acetylpyridine on treatment with methylmagnesium iodide and the acetylpyridine was subsequently treated with ethylmagnesium iodi...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/39234 |