AMP-activated protein kinase and hypertrophic remodeling of heart muscle cells

Introduction: Cardiac hypertrophy is an adaptive response to increased myocardial workload that becomes maladaptive when hypertrophied hearts are exposed to an acute metabolic stress, such as ischemia/reperfusion. Acceleration of glycolysis occurs as part of the hypertrophic response and may be mala...

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Bibliographic Details
Main Author: Saeedi, Ramesh
Format: Others
Language:English
Published: University of British Columbia 2009
Subjects:
Online Access:http://hdl.handle.net/2429/4065