Studies in phagosome maturation : modulation by both the host phosphatidylinositol 3-kinase p110alpha and the mycobacterial protein PE-PGRS62
Phagosome maturation is a key innate immune response involving interactions of phagosomes with the endosomal system. These interactions result in the creation of a destructive, antimicrobial phagolysosome compartment. How this process is regulated is not entirely known, and intracellular pathogens s...
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| Language: | English |
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University of British Columbia
2012
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| Online Access: | http://hdl.handle.net/2429/43699 |