Defects in messenger RNA processing and biogenesis of RNA polymerases contribute to eukaryotic genome instability
Genome instability has been observed in mutants involved in various aspects of transcription and RNA processing. The prevalence of this mechanism among essential chromosome instability (CIN) genes remains unclear. In this thesis, it is shown that RNA biogenesis mutants exhibit elevated sensitivity...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2013
|
| Online Access: | http://hdl.handle.net/2429/44216 |