Oligomerization dependent enzyme kinetics and mechanistic characterization of type I protein arginine N-methyltransferases
Protein arginine N-methyltransferases (PRMTs) constitute a family of post-translational modifying enzymes that modulate protein-protein interactions via the addition of methyl groups to arginine residues in protein substrates (1). PRMTs have been demonstrated to homooligomerize via a dimerization ar...
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| Language: | English |
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University of British Columbia
2013
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| Online Access: | http://hdl.handle.net/2429/44623 |