Inference of rates across sites via an expectation maximization algorithm

The rates of nucleotide substitution can be different from genes to genes. Moreover, different regions of the same gene can have different rates of mutation as well. Many attempts have been tried to allow for the variable rates across different nucleotide sites. A rate factor coming from the contin...

Full description

Bibliographic Details
Main Author: Zhao, Tingting
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44930