The role of interactions between 4N1K and CD47 on integrin activation and integrin-mediated cell adhesion

Integrins are heterodimeric, cell-surface receptors that play a role in adhesion and chemoresistance. Integrins can be found in one of two states: an inactivated state where integrin-mediated adhesion is not supported, or in an activated state where integrin-mediated adhesion is possible. CD47 is a...

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Bibliographic Details
Main Author: Leclair, Pascal
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/47040