Binding and structural insights of the ryanodine receptor

Ryanodine Receptors (RyR) are large ion channels that are responsible for the release of Ca²⁺ from the sarco/endoplasmic reticulum. The channel consists of a large cytosolic cap which functions as a giant allosteric protein, capable of being modulated by an assortment of binding partners and small m...

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Bibliographic Details
Main Author: Lau, Kelvin
Language:English
Published: University of British Columbia 2014
Online Access:http://hdl.handle.net/2429/50503