Ocular melanocytes respond to oncogenic GNAQQ209L differently compared to epidermal and dermal melanocytes in mice
Somatic mutations in the homologous human oncogenes GNAQ, and GNA11, are frequently found in ocular melanomas of the uvea, blue nevi of the dermis, and melanocytic neoplasias of the central nervous system (CNS), but rarely in cutaneous melanoma located in the epidermis (0.3%). The most common mutati...
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| Language: | English |
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University of British Columbia
2015
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| Online Access: | http://hdl.handle.net/2429/51763 |