Unraveling the role of Gp78/AMFR : an E3 ubiquitin ligase and cell surface receptor, in cancer progression
Background/Aim: This thesis focuses on the role of Gp78/AMFR in cancer progression by (1) investigating the relationship between the dual functions of Gp78/AMFR as a cell surface receptor and intracellular ubiquitin ligase in ERAD; (2) unraveling the post-translational modification (PTM) of Gp78/AMF...
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| Language: | English |
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University of British Columbia
2015
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| Online Access: | http://hdl.handle.net/2429/52321 |