Extracellular Granzyme K mediates endothelial inflammation through the cleavage of Protease Activated Receptor-1

Granzymes are a family of serine proteases that were once thought to function exclusively as mediators of cytotoxic lymphocyte-induced target cell death. However, non-lethal roles for granzymes, including Granzyme K (GzK), have been recently proposed. As recent studies have observed elevated levels...

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Bibliographic Details
Main Author: Sharma, Mehul
Language:English
Published: University of British Columbia 2015
Online Access:http://hdl.handle.net/2429/55402