Characterization of novel therapeutic targets in chronic myeloid leukemia

The identification of BCR-ABL1 as the key molecular event in chronic myeloid leukemia (CML) has revolutionized treatment opportunities for early phase patients. Imatinib mesylate (IM) and other ABL1 tyrosine kinase inhibitors (TKIs) have been introduced into the clinic with remarkable effects. Howev...

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Bibliographic Details
Main Author: Rothe, Katharina
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/56175