Development and evaluation of a novel approach to producing uniform 3-D tumor spheroid constructs

In vitro tumor spheroid models have been developed using microfluidic systems to generate 3-D hydrogel beads containing components of alginate and ECM protein, such as collagen, with high uniformity and throughput. During bead gelation, alginate acts as a fast gelling component helping to maintain t...

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Bibliographic Details
Main Author: Karamikamkar, Solmaz
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/56296