Molecular mechanism of cyclic nucleotide action on HCN pacemaker channels
HCN pacemaker channels generate the “funny” current that is responsible for initiation and regulation of electrical activity in the heart and the nervous system. Activated near resting membrane potentials, the channel conducts a net inward current that maintains action potential. The direct binding...
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
University of British Columbia
2016
|
| Online Access: | http://hdl.handle.net/2429/57686 |