Overcoming missing data in phylogenetic analysis of shotgun sequencing to detect HIV adaptation to immune response
DNA sequencing gives us insight into how viruses adapt to their host immune systems. Studies of viral populations typically employ deep amplicon sequencing with next-generation reads to capture a detailed sample of genetic variation in a population. The high amount of overlapping sites in a multiple...
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| Language: | English |
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University of British Columbia
2016
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| Online Access: | http://hdl.handle.net/2429/59108 |