Prevention of type 1 diabetes by carbamazepine in non-obese diabetic mice

Pancreatic β cells are selectively destroyed by the host immune system in type 1 diabetes, which results in the inability to regulate glucose homeostasis due to loss of insulin production capacity. Drugs that preserve β cell mass and function therefore have the potential to prevent or slow the progr...

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Bibliographic Details
Main Author: Lee, Jason Tsz Chun
Language:English
Published: University of British Columbia 2017
Online Access:http://hdl.handle.net/2429/62704