Effects of direct active-site anticoagulants on the fibrinolytic function of coagulation factor Xa

Treatment of occlusive clots (thrombi) is important for proper health yet systemic bleeding remains a major complication of thrombolytic therapy. Thus, the utility of agents such as alteplase, the current thrombolytic approved to rapidly lyse thrombi, is limited. As an alternative, our laboratory ha...

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Bibliographic Details
Main Author: Carter, Rolinda Louise Raphaelle
Language:English
Published: University of British Columbia 2017
Online Access:http://hdl.handle.net/2429/63386