Investigation of the effect of in vivo inhibition of dipeptidyl peptidase IV (DP IV) on glucose tolerance in Zucker rats and of DP IV expression in pancreatic beta cells

Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are two hormones released from the gut post-prandially which act at the pancreatic β cell to potentiate glucose-induced insulin secretion. DP IV is the primary enzyme responsible for the cleavage and inactivati...

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Bibliographic Details
Main Author: White, Heather Ann
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/8349