Contribution of non-centrosomal microtubules to mitotic spindle assembly in mammalian cells

In mammalian cells, the formation of a bipolar spindle is an essential process as any mistake in the segregation of chromosomes can result in aneuploidy, an outcome that can be detrimental to the organism. Microtubules are the key structures required for the success of this operation, as they are th...

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Bibliographic Details
Main Author: Tulu, Ustun Serdar
Language:ENG
Published: ScholarWorks@UMass Amherst 2007
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3275811