Studies of initiation and elongation in T7 RNA polymerase

During transcription initiation, competition between the initiation and elongation processes is thought to lead to the production of abortive transcripts (2–8 nucleotides of RNA) by the RNA polymerases. Our results show that A-16C and T-14G promoter mutations would lead to earlier promoter escape ev...

Full description

Bibliographic Details
Main Author: Enuameh, Metewo Selase
Language:ENG
Published: ScholarWorks@UMass Amherst 2008
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3325119