The role of the ER glucosyltransferase in the quality control of glycoprotein maturation
N-linked glycans serve as quality control tags in the eukaryotic secretory pathway. The endoplasmic reticulum (ER) protein UDP-glucose: glycoprotein glucosyltransferase 1 (GT1) is the main enzyme that modifies carbohydrate tags based upon the folding state of the maturing substrate. GT1 adds glucose...
| Main Author: | |
|---|---|
| Language: | ENG |
| Published: |
ScholarWorks@UMass Amherst
2009
|
| Subjects: | |
| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3380004 |