The conformational gymnastics of the Escherichia coli SecA molecular machine and its interactions with signal sequences

Protein secretion is a selective and regulated process that is essential in all organisms. In bacteria the preprotein translocase SecA, either free in the cytosol or associated with the SecYEG translocon, recognizes and binds most post-translational secretory proteins containing an N-terminal signal...

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Bibliographic Details
Main Author: Maki, Jenny Lynn
Language:ENG
Published: ScholarWorks@UMass Amherst 2009
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3372265