The roles of Notch1 and PKC-Θ in immune mediated bone marrow failure
We sought to evaluate the individual contributions of Notch1 and PKC-Theta to disease progression in a mouse model of immune-mediated bone marrow failure and to define a mechanism for their potential cellular cooperation. We transferred parental bulk splenocytes into F1-hybrid recipients to induce a...
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Language: | ENG |
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ScholarWorks@UMass Amherst
2011
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Online Access: | https://scholarworks.umass.edu/dissertations/AAI3465077 |