Molecular mechanisms regulating complement receptor 3-mediated phagocytosis of Borrelia burgdorferi
The macrophage receptors that mediate phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, are unknown despite this cell type’s importance in promoting pathogen clearance and inflammation-mediated tissue damage. We now demonstrate that the β2 integrin, Complement Receptor 3 (CR3), medi...
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Language: | ENG |
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ScholarWorks@UMass Amherst
2012
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Online Access: | https://scholarworks.umass.edu/dissertations/AAI3545936 |