Molecular mechanisms regulating complement receptor 3-mediated phagocytosis of Borrelia burgdorferi

The macrophage receptors that mediate phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, are unknown despite this cell type’s importance in promoting pathogen clearance and inflammation-mediated tissue damage. We now demonstrate that the β2 integrin, Complement Receptor 3 (CR3), medi...

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Bibliographic Details
Main Author: Hawley, Kelly L
Language:ENG
Published: ScholarWorks@UMass Amherst 2012
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3545936