RecA dynamics & the SOS response in Escherichia coli: Cellular limitation of inducing filaments

During the course of normal DNA replication, replication forks are constantly encountering "housekeeping" types of routine damage to the DNA template that may cause the forks to stall or collapse. One product of this fork collapse is the induction of the SOS response, a coordinated global...

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Bibliographic Details
Main Author: Massoni, Shawn Christopher
Language:ENG
Published: ScholarWorks@UMass Amherst 2013
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3556269