Structural and biochemical studies of the human lysosomal enzymes: N-acetylgalactosamine-6-sulfatase, N-sulfoglucosamine sulfohydrolase and β-galactosidase
Lysosomal storage diseases are disorders caused by deficiencies of enzymes responsible for the degradation of substances present in lysosomes. The loss of activity of a lysosomal enzyme leads to the accumulation of substrates within the lysosome, which is the initial step in the process leading to a...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2013
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3589159 |