Regulation of Eg5 and TPX2 during mammalian mitosis

During mitosis, the microtubule cytoskeleton is completely rearranged to form a bipolar spindle that functions to congress and segregate a complete set of genetic material into two nascent daughter cells. The kinesin-5 family of molecular motor proteins is required for spindle pole separation in mos...

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Bibliographic Details
Main Author: Titus, Janel
Language:ENG
Published: ScholarWorks@UMass Amherst 2013
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3603165