THE FAR C-TERMINUS OF TPX2 CONTRIBUTES TO SPINDLE MORPHOGENESIS

THE FAR C-TERMINUS OF TPX2 CONTRIBUTES TO SPINDLE MORPHOGENESIS

A cell must build a bipolar mitotic spindle in order to faithfully segregate replicated DNA. To do so, multiple microtubule nucleation pathways are utilized to generate the robust spindle apparatus. TPX2, a microtubule binding protein, holds crucial roles in both the Ran-dependent and Augmin-depende...

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Bibliographic Details
Main Author: Estes, Brett
Format: Others
Published: ScholarWorks@UMass Amherst 2017
Subjects:
TPX2
Augmin
Spindle Assembly
Mitotic Spindle
Microtubules
Cell Biology
Online Access:https://scholarworks.umass.edu/masters_theses_2/462
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1508&context=masters_theses_2

Internet

https://scholarworks.umass.edu/masters_theses_2/462
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1508&context=masters_theses_2

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