The SHAPE of U: Mapping Out Protective Elements in mRNA Escapees
A crucial step of the viral life cycle of Kaposi’s Sarcoma Herpesvirus (KSHV) lytic infection is the triggering of a massive RNA decay event termed “Host Shutoff”. Host Shutoff is driven by the viral endonuclease SOX which leads to the destruction of over 70% of the total transcriptome. This process...
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ScholarWorks@UMass Amherst
2020
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| Online Access: | https://scholarworks.umass.edu/masters_theses_2/977 https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=2052&context=masters_theses_2 |