The Role of Runx1 N-Terminal Splice Isoforms in Hematopoietic Development

Runx1/AML1 transcription factor expression in hematopoietic cell lineages is differentially regulated via usage of two distinct promoters. The 5' UTR and a 19 amino acid encoding sequence transcribed from the distal promoter is inserted via alternative splicing into the 5' end of the mRNA...

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Bibliographic Details
Main Author: Hedblom, Emmett E.
Format: Others
Published: ScholarWorks@UMass Amherst 2010
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Online Access:https://scholarworks.umass.edu/open_access_dissertations/175
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1181&context=open_access_dissertations