Notch 1 Mediated Inhibition of Nur77-induced apoptosis: Implications for T-cell Leukemia
It is widely accepted that activating mutations of genes encoding the Notch family of transmembrane receptors, specifically Notch1, are associated with oncogenic transformation. Previous data from our lab has shown that an active form of Notch1 (NICD) provides protection against apoptosis in D011.10...
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ScholarWorks@UMass Amherst
2010
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| Online Access: | https://scholarworks.umass.edu/open_access_dissertations/253 https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1203&context=open_access_dissertations |