Development and Characterization of Caspase Activatable GFP and a Family of Fluorescent Reporters

The cellular process of programmed cell death, or apoptosis, is critical in homeostasis and development. In addition it's misfunction is implicated in an array of disease states from cancer to neurodegeration, making it an attractive pathway for drug targeting. A family of proteases, known as c...

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Bibliographic Details
Main Author: Nicholls, Samantha Elizabeth Bernard
Format: Others
Published: ScholarWorks@UMass Amherst 2013
Subjects:
GFP
Online Access:https://scholarworks.umass.edu/open_access_dissertations/721
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1729&context=open_access_dissertations