Probing the Peptidyl Transferase Center of Ribosomes Containing Mutant 23s rRNA with Photoreactive tRNA
There is strong crystallographic evidence that the 23S rRNA is the only catalytic entity in the peptidyl transferase center. Various mechanisms for the catalysis of peptidyl transfer have been proposed. Recently, attention has been given to the idea that the 23S rRNA simply acts to position the tR...
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ScholarWorks@UMass Amherst
2008
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| Online Access: | https://scholarworks.umass.edu/theses/87 https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1127&context=theses |