Investigating the Mechanism of Nur77-Induced Apoptosis in T Cells

Nur77 is a member of the orphan nuclear receptor family, where it is known to play an important role in apoptosis in both negative selection in T cells and in cancer cell lines. In the development of T cells, it is critical for the immune system to discriminate self from non-self by eliminating auto...

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Bibliographic Details
Main Author: Fogarty, Heather E.
Format: Others
Published: ScholarWorks@UMass Amherst 2012
Subjects:
Online Access:https://scholarworks.umass.edu/theses/761
https://scholarworks.umass.edu/cgi/viewcontent.cgi?article=1864&context=theses