The Outer Limits: Telomere Maintenance by TRF2 and G-Quadruplex DNA Structures
Human telomeric DNA consists of tandem repeats of the sequence 5'-d(TTAGGG)-3' assembled into a nucleoprotein complex that functions to protect the ends of chromosomes. Such guanine-rich DNA is capable of forming a variety of G-quadruplexes, which in turn, can have varying functional conse...
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| Format: | Others |
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Scholarly Repository
2008
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| Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/24 |