The Story of the Promiscuous Substrate: An Investigation of the Role of the PI3K Pathway in p27Kip1 Regulation
Deregulated cell proliferation, resulting from disruption of cell cycle control, is characteristic of many cancers. In normal cells, cell cycle progression is mediated by a family of cyclin dependent kinases (Cdks) that are positively regulated by associated cyclins. The activities of these cyclin...
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| Format: | Others |
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Scholarly Repository
2008
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| Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/36 |