Regulation of HSC Self-Renewal and Differentiation by Pumilio Proteins
Evolutionarily conserved Pumilio (Pum) RNA-binding proteins act as translational repressors during embryo development and cell fate specification. Previous work in the lab has shown that over-expression of Pum2 (Pum2-EML) supports maintenance and suppresses mutilineage differentiation of murine mult...
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| Format: | Others |
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Scholarly Repository
2008
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| Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/300 |