MCP-1 Induces Rapid Formation of Tethered VLA-4 Bonds with Increased Resistance to Applied Forcein THP-1 Cells
The chemokine, Monocyte Chemoattractant Protein (MCP-1), enhances integrin mediated monocyte adhesion to the vascular endothelium during inflammation. In this study, we demonstrate that MCP-1 promotes rapid sub-second adhesion of THP-1 cells to Vascular Cell Adhesion Molecule-1 (VCAM-1), but not to...
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| Format: | Others |
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Scholarly Repository
2011
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| Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/592 |