p27 and Metastatic Progression: Molecular Mechanisms Underlying Bone Metastasis

The complex PI3K/mTOR pathway regulates tumor progression via effects on cellular proliferation, apoptosis, autophagy, and motility. New drugs that inhibit the catalytic site of both PI3K and mTOR have shown promise in clinical trials. Here, we report the first use of a novel, dual PI3K/mTOR catalyt...

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Bibliographic Details
Main Author: Wander, Seth A
Format: Others
Published: Scholarly Repository 2011
Subjects:
p27
Online Access:http://scholarlyrepository.miami.edu/oa_dissertations/690