High cell density perfusion process development for antibody producing Chinese Hamster Ovary cells
Perfusion operation mode is currently under fast expansion in mammalian cell based manufacturing of biopharmaceuticals, not only for labile drug protein but also for stable proteins such as monoclonal antibodies (mAbs). Perfusion mode can advantageously offer a stable cell environment, long-term pro...
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| Format: | Doctoral Thesis |
| Language: | English |
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KTH, Industriell bioteknologi
2017
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-207600 http://nbn-resolving.de/urn:isbn:978-91-7729-450-4 |