A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases

A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases

This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification. A novel, user-friendly, and efficient meth...

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Bibliographic Details
Main Author: Viljanen, Johan
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Organisk Kemi 2008
Subjects:
Human GST A1-1
site-specific covalent modification
tyrosine 9
lysine 216
methionine 208
multipurpose receptor
pattern recognition
protein purification
Chemistry
Kemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11612
http://nbn-resolving.de/urn:isbn:978-91-7393-893-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11612
http://nbn-resolving.de/urn:isbn:978-91-7393-893-8

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