Importance of microenvironment and antigen in the regulation of growth and survival of CLL cells

Chronic lymphocytic leukemia (CLL) cells rapidly die when put in culture implying that microenvironmental signals delivered by accessory cells confer CLL cells with a growth advantage. Recent findings show that CLL cells are antigen experienced and antigen binding play a critical role in the pathoge...

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Bibliographic Details
Main Author: Bergh, Ann-Charlotte
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Avdelningen för cellbiologi 2016
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-124576
http://nbn-resolving.de/urn:isbn:978-91-7685-867-7