Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17θ-estradiol

CD4+CD25high regulatory T cells (Tregs) are implicated in the maintenance of murine pregnancy. However, reports regarding circulating Treg frequencies in human pregnancy are inconsistent, and the functionality and phenotype of these cells in pregnancy have not been clarified. The aim of this study w...

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Bibliographic Details
Main Authors: Mjösberg, Jenny, Svensson, Judit, Johansson, Emma, Hellström, Lotta, Casas, Rosaura, Jenmalm, Maria, Boij, Roland, Matthiesen, Leif, Jönsson, Jan-Ingvar, Berg, Göran, Ernerudh, Jan
Format: Others
Language:English
Published: Linköpings universitet, Klinisk immunologi 2009
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-53104