Utveckling och validering av en LC-MS/MS metod för kvantifiering av clopidogrel och dess metabolit i plasma

Clopidogrel is an antiplatelet substance that prevents blood coagulation in the arteries. It is an inactive pro drug that becomes activated after first-pass metabolism by the liver. The active metabolite of clopidogrel is 2-oxoclopidogrel, which is unstable therefore pharmacokinetic data is obtained...

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Bibliographic Details
Main Author: Shamon, Doreen-Marie
Format: Others
Language:Swedish
Published: Linköpings universitet, Institutionen för fysik, kemi och biologi 2010
Subjects:
SRM
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-58731