Nucleoside analoge cytotoxicity-focus on enzyme regulation, metabolism, and mechanisms of resistance
The aim of this thesis was to determine the role of nucleoside analog activating and deactivating enzymes in nucleoside analog metabolism and resistance development. Nucleoside analogs are anti-cancer drogs and are often used to treat different leukemias, attributably to presence of high levels of n...
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| Format: | Doctoral Thesis |
| Language: | English |
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Linköpings universitet, Klinisk farmakologi
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-63247 http://nbn-resolving.de/urn:isbn:978-91-7393-310-0 |