Interaction between insulin and IGF-I receptors in insulin sensitive and insulin resistant cells and tissues

Insulin and insulin-like growth factor I (IGF-I) are two related peptides with similar structure. They mediate their effects by binding to their respective receptor, the insulin receptor (IR) and the IGF-I receptor (IGF-IR) and induce intracellular signalling cascades resulting in metabolic or mitog...

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Bibliographic Details
Main Author: Bäck, Karolina
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Cellbiologi 2011
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71892
http://nbn-resolving.de/urn:isbn:978-91-7393-042-0