Chitosan-based nanocarriers for gene- and siRNA-delivery

Gene therapy is promising for the treatment of many currently incurable diseases by delivering or silencing specific genes with pDNA or siRNA, respectively. Clinical trials have mostly been conducted with viral or relatively toxic nonviral nucleic acid delivery systems. The biopolymer chitosan have...

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Bibliographic Details
Main Author: Malmo, Jostein
Format: Doctoral Thesis
Language:English
Published: Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi 2012
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-17702
http://nbn-resolving.de/urn:isbn:978-82-471-3746-8 (printed ver.)
http://nbn-resolving.de/urn:isbn:978-82-471-3748-2 (electronic ver.)