Genetic variation in the folate receptor-alpha and methylenetetrahydrofolate reductase genes as determinants of plasma homocysteine concentrations
Elevated total plasma homocysteine (tHcy) is a risk factor for cardiovascular disease and neurocognitive disease such as dementia. The B vitamins folate and B12 are the main de terminants of tHcy. tHcy concentration can also be affected by mutations in genes coding for receptors, enzymes and transpo...
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Format: | Doctoral Thesis |
Language: | English |
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Örebro universitet, Hälsoakademin
2008
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-2625 http://nbn-resolving.de/urn:isbn:978-91-7668-642-3 |