In situ Sequencing : Methods for spatially-resolved transcriptome analysis

It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently,...

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Bibliographic Details
Main Author: Mignardi, Marco
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för biokemi och biofysik 2014
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-110057
http://nbn-resolving.de/urn:isbn:978-91-7649-066-2